Current projectsInternet research turned up a reference to work done at Purdue Veterinary School by Dr. Kevin Hahn in which a biopsy tool was used to drill through the bone so that drugs could be delivered directly to the tumor site. Even with the somewhat crude tools available at the time, the results were promising. This suggested the possibility that such an approach could offer a more reliable treatment than limb isolation (which often proves impossible in dogs because of problems with the arterial cannula) while still providing the benefit of reduction or elimination of side effects. We are working on such a targeted delivery of radioisotopes in partnership with IsoTherapeutics Group, LLC. Critical to success is the development of a more sophisticated tool for bone penetration. We are currently conducting tests with a prototype bone drill capable of drilling a clean .017" hole through a rodent femur, and have applied for U.S. and international patents. |